Hydrogen peroxide participates in perception and transduction of cold stress signal in synechocystis

Pavel V. Fedurayev, Kirill S. Mironov, David A. Gabrielyan, Vladimir S. Bedbenov, Anna A. Zorina, Maria Shumskaya, Dmitry A. Los

Research output: Contribution to journalArticlepeer-review

17 Scopus citations

Abstract

The double mutant ΔkatG/tpx of cyanobacterium Synechocystis sp. strain PCC 6803, defective in the anti-oxidative enzymes catalase (KatG) and thioredoxin peroxidase (Tpx), is unable to grow in the presence of exogenous H2O2. The ΔkatG/tpx mutant is shown to be extremely sensitive to very low concentrations of H2O2, especially when intensified with cold stress. Analysis of gene expression in both wild-type and ΔkatG/tpx mutant cells treated by combined cold/oxidative stress revealed that H2O2 participates in regulation of expression of cold-responsive genes, affecting either signal perception or transduction. The central role of a transmembrane stress-sensing histidine kinase Hik33 in the cold/oxidative signal transduction pathway is discussed.

Original languageEnglish
Pages (from-to)1255-1264
Number of pages10
JournalPlant and Cell Physiology
Volume59
Issue number6
DOIs
StatePublished - 1 Jun 2018

Keywords

  • Cold stress
  • Hydrogen peroxide
  • Oxidative stress
  • ROS
  • Synechocystis

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