A cost-efficient design for microarray image system

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Abstract

Image based Microarray processing has been widely applied to the biotechnology field for identifying SNP variations. In order to reduce the cost for manufacturers, a flexible design for handling different layouts of containers and different numbers of spots is necessary to accomplish the need for different throughputs on the same microarray instrument. The key to making the microarray technology successful is spot recognition during the image processing. There are many factors that could affect the quality and alignment of spots. Both high accuracy and automation in spot intensity acquisition is required to have a correct result. Here, we present a cost-efficient design that will accommodate for different spot layouts with minimal required information.

Original languageEnglish
Title of host publicationProceedings - 2015 International Conference on Computational Science and Computational Intelligence, CSCI 2015
EditorsQuoc-Nam Tran, Leonidas Deligiannidis, Hamid R. Arabnia
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages515-518
Number of pages4
ISBN (Electronic)9781467397957
DOIs
StatePublished - 2 Mar 2016
EventInternational Conference on Computational Science and Computational Intelligence, CSCI 2015 - Las Vegas, United States
Duration: 7 Dec 20159 Dec 2015

Publication series

NameProceedings - 2015 International Conference on Computational Science and Computational Intelligence, CSCI 2015

Conference

ConferenceInternational Conference on Computational Science and Computational Intelligence, CSCI 2015
Country/TerritoryUnited States
CityLas Vegas
Period7/12/159/12/15

Keywords

  • Container
  • Controls
  • Layout
  • Microarray
  • SNP
  • Spots

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